Device for Streptavidin Detection Using LSPR and Electrochemical Transductions on the same Platform

Research in biosensing currently occupies an important role among biomolecular detection techniques, especially with respect to medical diagnoses. Is this sense, the development of biosensors based on localized surface plasmon resonance (an optical transducer) or electrochemical transductions have been highlighted. However, and working together enable more versatile detections biosensing. Thus, we propose a dual sensor, which incorporates these two mechanisms same platform. The sensor shared transducer that was glass-indium thin oxide (ITO) covered gold nanoparticles. prepared by immobilization nanoparticles (3-aminopropyl)triethoxysilane-activated glass-ITO. substrate ability respond physical variations assessed. For this, measurements band redshift (plasmonic transduction) charge transfer resistance from impedance spectra (electrochemical were performed. platform able detect streptavidin immobilized both demonstrating its applicability as device for biodetection mode.